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Richard Ramonell, MD
University of Pittsburgh
Editor, ATS Asthma Center
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Cleveland Clinic
Editor, ATS Asthma Center
Jyoti Lenka MD, MBBS
University of Connecticut
Editor, ATS Asthma Center
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On Sept. 7, 2023, a new working definition for clinical remission on treatment in asthma was published in Annals of Allergy, Asthma & Immunology. The consensus paper is a product of the American College of Allergy, Asthma & Immunology (ACAAI), the American Academy of Allergy, Asthma & Immunology (AAAAI), and the American Thoracic Society (ATS). It is endorsed by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA).
As an increasing number of improved asthma treatments are developed, a greater number of people with asthma are finding that their symptoms are under control. Their improved status raises an important question for health care providers (HCPs) who treat this condition: “What qualifies as clinical remission in asthma treatment?”
The leadership of ACAAI convened a panel of 11 experts in asthma care in association with AAAAI and ATS to review available literature and create the definition of clinical remission on treatment in asthma. The panel included six allergists, three pulmonologists, and two pediatricians.
The authors note that this document is a jumping-off point and a template to allow for further clinical research. They also commented that HCPs treating asthma patients can use this definition to generate needed data. The definition is expected to evolve over time.
As the term “remission” has historically implied total control of asthma, without medication use, the workgroup proposed six criteria for asthma clinical remission on treatment. Of the six criteria, three had unanimous consent, while the remaining three had factors that remain under consideration. Read more here.