Answer C. Pneumomediastinum
Discussion
Bronchial diverticula are projections or outpouching that are still
considered as incidental and rare findings. The patients do not present
with any type of symptomatology, and it has been associated with
patients who have Chronic Obstructive Pulmonary Disease (COPD) (1).
Literature has described the presence of tracheal diverticula as
well, and between the bronchial and tracheal, the latter has been the
most common. (1,2). These outpouching have been described to be
congenital or acquired. (3)
Congenital diverticula are considered a remnant of an accessory
bronchus that are most likely located in the right mainstem bronchus or
the lower trachea. (3) The congenital diverticula affect not only the
respiratory epithelium, but also the smooth muscle and the cartilage; as
seen on the congenital tracheal diverticula. (4)
The acquired
diverticula are related to weakness in the wall, secondary to chronic
pulmonary conditions, surgical procedures or tracheomalacia. (3,4). The
outpouching of an acquired diverticula only includes the respiratory
epithelium; as reported on the acquired tracheal diverticula. (4)
In 2012, a study in Italy was conducted to determine the prevalence
of bronchial diverticula in non-smokers. 121 patients were enrolled,
they were non-smoker participants, who had a referral to get a chest
computed tomography (CT) for different reasons. (5) Most importantly,
these patients did not have any respiratory symptoms when undergoing
computed tomography (CT). The study reported a prevalence of 33.9%; more
present in males than females, and with the right main bronchi more
involved. (5)
Even though the study mentioned above showed a
prevalence of 33.9%, there is no no clear prevalence of this rare
disease. There have been many studies that have shown different values.
(6) These different percentages have been influenced by the type of
population enrolled, for example smokers vs non-smokers. It seems that
patients who have a history of smoking have a higher risk of acquiring a
bronchial diverticula when compared to those who did not smoke. (7)
Regarding bronchial diverticula, the most common location as
mentioned above has been the subcarinal region of the right main
bronchi. (3,8) and it has been related to patients with Chronic
Obstructive Pulmonary Disease (COPD), but few studies have been proven
otherwise. These studies have also shown that the presence of
diverticula is not a criterion for Chronic Obstructive Pulmonary Disease
(COPD). (2,3,8).
In this case report, the theory was thought to be a congenital
diverticula. Since the diverticula is located in the right main bronchus
where most of the congenital bronchial diverticula have been reported.
Also, the patient did not have a past medical history of Chronic
Obstructive Pulmonary Disease (COPD) or any other type of chronic
respiratory disease. This conclusion is based only on the patient's
history, physical exam and early imaging, since we do not count with a
bronchoscopy examination.
As seen in this case, bronchial diverticula may mimic other more
serious entities such as pneumomediastinum. But not all cases of air
locules outside of the trachea and bronchi are true pneumomediastinum,
it will depend on the presentation of the patient. It is highly
recommended to suspect other etiologies that are benign in nature, such
as congenital bronchial diverticula. This is very important, to minimize
unnecessary procedures and or radiation exposure, that is very well
known to be related to increased morbidity and mortality.
Bronchial diverticula are mostly an incidental finding on chest
computed tomography (CT), which is the best imaging modality to detect
them. These diverticula are either congenital or acquired asymptomatic
projections of the bronchi, and when acquired they have been highly
associated with smoking.
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