The authors and expert panel will discuss a recent article and the impact on clinical management of patients with complicated pleural infections. Eihab Bedawi, PhD, MRCP, University of Sheffield, and Najib Rahman, DPhil, MSc, FRCP, University of Oxford, will present their article, "Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial—MIST-3," published recently in the American Journal of Respiratory and Critical Care Medicine.