Convergent and Divergent Immune Aberrations in COVID-19, post-COVID-19-Interstitial Lung Disease, and Idiopathic Pulmonary Fibrosis

During this journal club, Bochra Tourki, PhD will present the recently published American Journal of Physiology Cell Physiology article investigating transcriptional and phenotypic changes in peripheral immune cells in over 200 patients with COVID-19, post-COVID-19 interstitial lung disease (ILD), idiopathic pulmonary fibrosis (IPF), and controls. The authors identified the presence of three genomic risk profiles in COVID-19 based on the 50-gene signature associated with low-, intermediate-, or high-risk of mortality and with significant differences in proinflammatory and profibrotic cytokines. Following the presentation, there will be a panel discussion from experts in the field. The session will be moderated by Andrew Myers, MD.